BDBM50293280 3-(4-(hydroxymethyl)phenyl)-4-(4-(methylsulfonyl)phenyl)-1-propyl-1H-pyrrol-2(5H)-one::CHEMBL469785

SMILES CCCN1CC(=C(C1=O)c1ccc(CO)cc1)c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=HOQRPUGACQIBBI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293280   

TargetProstaglandin G/H synthase 2(Human)
Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50293280(3-(4-(hydroxymethyl)phenyl)-4-(4-(methylsulfonyl)p...)
Affinity DataIC50:  87nMAssay Description:Inhibition of LPS-induced COX2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mouse)
Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50293280(3-(4-(hydroxymethyl)phenyl)-4-(4-(methylsulfonyl)p...)
Affinity DataIC50:  87nMAssay Description:Inhibition of COX1 in mouse peritoneal macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mouse)
Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50293280(3-(4-(hydroxymethyl)phenyl)-4-(4-(methylsulfonyl)p...)
Affinity DataIC50:  14nMAssay Description:Inhibition of COX2 in mouse peritoneal macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed