BDBM50294115 CHEMBL550222::N-(4-(4-(2-(methylthio)phenyl)piperazin-1-yl)butyl)H-pyrazolo[1,5-a]pyridine-2-carboxamide

SMILES CSc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccn3n2)CC1

InChI Key InChIKey=DWEHMLBGRQZUJA-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50294115   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50294115(CHEMBL550222 | N-(4-(4-(2-(methylthio)phenyl)piper...)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50294115(CHEMBL550222 | N-(4-(4-(2-(methylthio)phenyl)piper...)
Affinity DataKi:  0.630nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50294115(CHEMBL550222 | N-(4-(4-(2-(methylthio)phenyl)piper...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50294115(CHEMBL550222 | N-(4-(4-(2-(methylthio)phenyl)piper...)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50294115(CHEMBL550222 | N-(4-(4-(2-(methylthio)phenyl)piper...)
Affinity DataKi:  65nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50294115(CHEMBL550222 | N-(4-(4-(2-(methylthio)phenyl)piper...)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed