BDBM50294213 3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2-hydroxy-3-methoxyphenyl)-1-(1-(4-(hydroxymethyl)phenyl)phthalazin-2(1H)-yl)prop-2-en-1-one::CHEMBL559830

SMILES COc1cc(Cc2cnc(N)nc2N)cc(\C=C\C(=O)N2N=Cc3ccccc3C2c2ccc(CO)cc2)c1O

InChI Key InChIKey=PVLCYETZWWPUKN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294213   

TargetDihydrofolate reductase(Human)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294213(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2-hydroxy...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed