BDBM50294546 4-[2-(9-Bromo-1-chloro-6,7-dihydro-12H-2,5,12-triaza-dibenzo[a,e]azulen-5-yl)-ethyl]-phenol::CHEMBL564679

SMILES Oc1ccc(CCN2CCc3c([nH]c4ccc(Br)cc34)-c3c(Cl)nccc23)cc1

InChI Key InChIKey=FNXISRZAOACOSB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50294546   

TargetInsulin receptor(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294546(4-[2-(9-Bromo-1-chloro-6,7-dihydro-12H-2,5,12-tria...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human recombinant IRKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294546(4-[2-(9-Bromo-1-chloro-6,7-dihydro-12H-2,5,12-tria...)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of recombinant METMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294546(4-[2-(9-Bromo-1-chloro-6,7-dihydro-12H-2,5,12-tria...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of 6xHis-tagged human NPM-ALK expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed