BDBM50294548 9-Bromo-1-chloro-5-[2-(1H-indol-3-yl)-ethyl]-5,6,7,12-tetrahydro-2,5,12-triaza-dibenzo[a,e]azulene::CHEMBL562943

SMILES Clc1nccc2N(CCc3c[nH]c4ccccc34)CCc3c([nH]c4ccc(Br)cc34)-c12

InChI Key InChIKey=BMXVTPILCBBLAF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50294548   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294548(9-Bromo-1-chloro-5-[2-(1H-indol-3-yl)-ethyl]-5,6,7...)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of 6xHis-tagged human NPM-ALK expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294548(9-Bromo-1-chloro-5-[2-(1H-indol-3-yl)-ethyl]-5,6,7...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of recombinant METMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294548(9-Bromo-1-chloro-5-[2-(1H-indol-3-yl)-ethyl]-5,6,7...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human recombinant IRKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed