BDBM50294783 3,3-Dimethyl-pentanedioic acid(5-carbamoyl-adamantan-2-yl)-amide cyclopropylamide::CHEMBL563234

SMILES CC(C)(CC(=O)NC1CC1)CC(=O)N[C@H]1C2CC3CC1C[C@](C3)(C2)C(N)=O

InChI Key InChIKey=VLDUQTLOJSSOIR-RXAJHBGNSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50294783   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50294783(3,3-Dimethyl-pentanedioic acid(5-carbamoyl-adamant...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as cortisol level after 150 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50294783(3,3-Dimethyl-pentanedioic acid(5-carbamoyl-adamant...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in Escherichia coli assessed as cortisol level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50294783(3,3-Dimethyl-pentanedioic acid(5-carbamoyl-adamant...)
Affinity DataIC50:  31nMAssay Description:Inhibition of 11beta-HSD1 in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50294783(3,3-Dimethyl-pentanedioic acid(5-carbamoyl-adamant...)
Affinity DataIC50:  10nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed