BDBM50295053 (S)-2-((4-(1H-Indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)-methyl)-8-methyl-2,3-dihydro-[1,4]dioxino-[2,3-f]quinoline::CHEMBL562248
SMILES Cc1ccc2c3O[C@@H](CN4CCC(=CC4)c4c[nH]c5ccccc45)COc3ccc2n1
InChI Key InChIKey=UIMJQPQEOBBSKO-IBGZPJMESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50295053
Affinity DataKi: 2.34nMAssay Description:Displacement of [3H]paroxetine from 5HT transporter in rat cortical membraneMore data for this Ligand-Target Pair
Affinity DataKi: 3.02nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 145nMAssay Description:Antagonist activity at human 5HT transporter expressed in staurosporine treated human JAR cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 56.7nMAssay Description:Antagonist activity at human 5HT1A receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair