BDBM50295754 (4-(1-(benzo[c][1,2,5]oxadiazol-4-ylsulfonyl)-1H-pyrrolo[3,2-b]pyridin-6-yl)piperazin-1-yl)(pyridin-3-yl)methanone::CHEMBL564904

SMILES O=C(N1CCN(CC1)c1cnc2ccn(c2c1)S(=O)(=O)c1cccc2nonc12)c1cccnc1

InChI Key InChIKey=WRYJHOBTINUUEH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50295754   Sort by

TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295754((4-(1-(benzo[c][1,2,5]oxadiazol-4-ylsulfonyl)-1H-p...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant His-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295754((4-(1-(benzo[c][1,2,5]oxadiazol-4-ylsulfonyl)-1H-p...)
Affinity DataIC50: 480nMAssay Description:Inhibition of c-Met phosphorylation in human MKN45 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295754((4-(1-(benzo[c][1,2,5]oxadiazol-4-ylsulfonyl)-1H-p...)
Affinity DataIC50: 430nMAssay Description:Inhibition of c-Met phosphorylation in human A549 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295754((4-(1-(benzo[c][1,2,5]oxadiazol-4-ylsulfonyl)-1H-p...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed