BDBM50295770 CHEMBL6074545

SMILES Cc1[nH]c(C(=O)Nc2ccc(-c3noc(=O)[nH]3)cc2N2CCCC(CN)C2)c(Cl)c1Cl

InChI Key InChIKey=PWDKVMAFPXGAFG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50295770   

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
University of Ljubljana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295770BDBM50295770(CHEMBL6074545)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
University of Ljubljana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295770BDBM50295770(CHEMBL6074545)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed