BDBM50295956 2-Chloro-3-(2-chloro-5-(pyridinyl)methoxy)-5-((1-methyl)-2-(S)-pyrrolidinyl)methoxy)pyridine::CHEMBL563831

SMILES CN1CCC[C@H]1COc1cnc(Cl)c(OCc2ccc(Cl)nc2)c1

InChI Key InChIKey=PLBWSQXHXCLSCU-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50295956   

TargetNeuronal acetylcholine receptor subunit alpha-2(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50295956(2-Chloro-3-(2-chloro-5-(pyridinyl)methoxy)-5-((1-m...)
Affinity DataKi:  0.0310nMAssay Description:Displacement of [3H]epibatidine from rat alpha2beta2 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50295956(2-Chloro-3-(2-chloro-5-(pyridinyl)methoxy)-5-((1-m...)
Affinity DataKi:  0.0550nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50295956(2-Chloro-3-(2-chloro-5-(pyridinyl)methoxy)-5-((1-m...)
Affinity DataKi:  0.260nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta2 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50295956(2-Chloro-3-(2-chloro-5-(pyridinyl)methoxy)-5-((1-m...)
Affinity DataKi:  6.60nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta4 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50295956(2-Chloro-3-(2-chloro-5-(pyridinyl)methoxy)-5-((1-m...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]epibatidine from rat alpha2beta4 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50295956(2-Chloro-3-(2-chloro-5-(pyridinyl)methoxy)-5-((1-m...)
Affinity DataKi:  320nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta4 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed