BDBM50296250 (S,Z)-3-(2-hydroxy-5-(1-hydroxy-3-methylbutyl)-4-methoxyphenyl)acrylate::CHEMBL560175

SMILES COc1cc(O)c(\C=C/C(O)=O)cc1[C@@H](O)CC(C)C

InChI Key InChIKey=KXEZMFMTEVLUPQ-ZFDPJTLLSA-N

Data  13 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50296250   

TargetCarbonic anhydrase 1(Human)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM50296250((S,Z)-3-(2-hydroxy-5-(1-hydroxy-3-methylbutyl)-4-m...)
Affinity DataIC50:  78nMAssay Description:Inhibition of human carbonic anhydrase 1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM50296250((S,Z)-3-(2-hydroxy-5-(1-hydroxy-3-methylbutyl)-4-m...)
Affinity DataIC50:  59nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 3(Human)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM50296250((S,Z)-3-(2-hydroxy-5-(1-hydroxy-3-methylbutyl)-4-m...)
Affinity DataIC50: >10nMAssay Description:Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 4(Human)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM50296250((S,Z)-3-(2-hydroxy-5-(1-hydroxy-3-methylbutyl)-4-m...)
Affinity DataIC50:  380nMAssay Description:Inhibition of human carbonic anhydrase 4 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 5A, mitochondrial(Human)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM50296250((S,Z)-3-(2-hydroxy-5-(1-hydroxy-3-methylbutyl)-4-m...)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of human carbonic anhydrase 5A by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 5B, mitochondrial(Human)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM50296250((S,Z)-3-(2-hydroxy-5-(1-hydroxy-3-methylbutyl)-4-m...)
Affinity DataIC50:  1.77E+4nMAssay Description:Inhibition of human carbonic anhydrase 5B by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 15(Mouse)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM50296250((S,Z)-3-(2-hydroxy-5-(1-hydroxy-3-methylbutyl)-4-m...)
Affinity DataIC50:  9.31E+4nMAssay Description:Inhibition of mouse carbonic anhydrase 15 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 7(Human)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM50296250((S,Z)-3-(2-hydroxy-5-(1-hydroxy-3-methylbutyl)-4-m...)
Affinity DataIC50:  2.79E+4nMAssay Description:Inhibition of human carbonic anhydrase 7 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 9(Human)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM50296250((S,Z)-3-(2-hydroxy-5-(1-hydroxy-3-methylbutyl)-4-m...)
Affinity DataIC50:  5.45E+4nMAssay Description:Inhibition of human carbonic anhydrase 9 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 12(Human)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM50296250((S,Z)-3-(2-hydroxy-5-(1-hydroxy-3-methylbutyl)-4-m...)
Affinity DataIC50:  4.86E+4nMAssay Description:Inhibition of human carbonic anhydrase 12 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 13(Mouse)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM50296250((S,Z)-3-(2-hydroxy-5-(1-hydroxy-3-methylbutyl)-4-m...)
Affinity DataIC50:  790nMAssay Description:Inhibition of mouse carbonic anhydrase 13 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 14(Human)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM50296250((S,Z)-3-(2-hydroxy-5-(1-hydroxy-3-methylbutyl)-4-m...)
Affinity DataIC50:  780nMAssay Description:Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 6(Human)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM50296250((S,Z)-3-(2-hydroxy-5-(1-hydroxy-3-methylbutyl)-4-m...)
Affinity DataIC50:  3.57E+4nMAssay Description:Inhibition of human carbonic anhydrase 6 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed