BDBM50296356 CHEMBL541762::N-(5-(5-(3,5-difluorophenylsulfonyl)-6,6-dimethyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-ylcarbamoyl)-2-(4-methylpiperazin-1-yl)phenyl)-1H-pyrrole-3-carboxamide

SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc[nH]c1)C(=O)Nc1[nH]nc2c1CN(C2(C)C)S(=O)(=O)c1cc(F)cc(F)c1

InChI Key InChIKey=JLIMOKFGZNPROX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296356   

TargetInsulin-like growth factor 1 receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296356(N-(5-(5-(3,5-difluorophenylsulfonyl)-6,6-dimethyl-...)
Affinity DataIC50: 90nMAssay Description:Inhibition of GST-tagged human IGF1R expressed in baculovirus-infected Sf21 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296356(N-(5-(5-(3,5-difluorophenylsulfonyl)-6,6-dimethyl-...)
Affinity DataIC50: 300nMAssay Description:Inhibition of IGF1R in IGF1-stimulated human MCF7 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed