BDBM50296754 CHEMBL558647::N-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl)pyrrolidin-2-yl)methyl)-N-cyclopropyl-1,1,1-trifluoromethanesulfonamide

SMILES N[C@@H](CC(=O)N1CCC[C@H]1CN(C1CC1)S(=O)(=O)C(F)(F)F)Cc1cc(F)c(F)cc1F

InChI Key InChIKey=LOTNXXFJKBJHID-OCCSQVGLSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50296754   

TargetCytochrome P450 2D6(Homo sapiens (Human))
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50296754(CHEMBL558647 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)
Affinity DataIC50:  100nMAssay Description:Inhibition of CYP2D6 in human human liver microsomes by mass spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50296754(CHEMBL558647 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of DPP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50296754(CHEMBL558647 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50296754(CHEMBL558647 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of human recombinant DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50296754(CHEMBL558647 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human recombinant DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed