BDBM50297389 3-(3-(tert-butylsulfonyl)-1-(4-(6-methoxypyridin-3-yl)benzyl)-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl)-2,2-dimethylpropanoic acid::CHEMBL538954

SMILES COc1ccc(cn1)-c1ccc(Cn2c(CC(C)(C)C(O)=O)c(c3cc(OCc4ccccn4)ccc23)S(=O)(=O)C(C)(C)C)cc1

InChI Key InChIKey=SWWQOAMPMCAOIU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297389   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297389(3-(3-(tert-butylsulfonyl)-1-(4-(6-methoxypyridin-3...)
Affinity DataIC50: 205nMAssay Description:Displacement of [3H]3-[5-(pyrid-2-ylmethoxy)-3-tert-butylthio-1-benzyl-indol-2-yl]-2,2-dimethylpropionic acid from FLAP in human polymorphonuclear ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed