BDBM50297649 5-chloro-6-oxo-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)-1,6-dihydropyridine-3-carboxamide::CHEMBL559691

SMILES O=C(NC1CCN(Cc2ccn(-c3ccc(C(F)(F)F)cc3)c2)CC1)c1c[nH]c(=O)c(Cl)c1

InChI Key InChIKey=XTKKCHSZIDZKRF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297649   

TargetMelanin-concentrating hormone receptor 1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297649BDBM50297649(5-chloro-6-oxo-N-(1-((1-(4-(trifluoromethyl)phenyl...)
Affinity DataIC50: 196nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50297649BDBM50297649(5-chloro-6-oxo-N-(1-((1-(4-(trifluoromethyl)phenyl...)
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed