BDBM50297674 4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidin-2-amine::CHEMBL558727

SMILES CS(=O)(=O)c1ccc(cc1)-c1cc(nc(N)n1)C(F)(F)F

InChI Key InChIKey=YSWMQMATRUHISF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297674   

TargetProstaglandin G/H synthase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50297674(4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)py...)
Affinity DataIC50:  272nMAssay Description:Inhibition of human COX2 expressed in baculovirus-infected SF9 cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50297674(4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)py...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human COX1 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 treated 1 hr before a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed