BDBM50297692 2-isopropoxy-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidine::CHEMBL551017

SMILES CC(C)Oc1nc(cc(n1)C(F)(F)F)-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=JUNZBTTUERRVNR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297692   

TargetProstaglandin G/H synthase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50297692(2-isopropoxy-4-(4-(methylsulfonyl)phenyl)-6-(trifl...)
Affinity DataIC50:  63nMAssay Description:Inhibition of human COX2 expressed in baculovirus-infected SF9 cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50297692(2-isopropoxy-4-(4-(methylsulfonyl)phenyl)-6-(trifl...)
Affinity DataIC50:  5.26E+4nMAssay Description:Inhibition of human COX1 expressed in baculovirus-infected SF9 cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed