BDBM50298516 5-[(4-Fluorobenzyl)carbonyl]amino-8-(3-phenylpropyl)-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine::CHEMBL574484

SMILES Fc1ccc(CC(=O)Nc2nc3nn(CCCc4ccccc4)cc3c3nc(nn23)-c2ccco2)cc1

InChI Key InChIKey=TWQZDHMGTHQJOG-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50298516   Sort by

TargetAdenosine receptor A2b(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50298516(5-[(4-Fluorobenzyl)carbonyl]amino-8-(3-phenylpropy...)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-induced adenylyl cyclase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50298516(5-[(4-Fluorobenzyl)carbonyl]amino-8-(3-phenylpropy...)
Affinity DataKi:  58.5nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50298516(5-[(4-Fluorobenzyl)carbonyl]amino-8-(3-phenylpropy...)
Affinity DataKi:  211nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50298516(5-[(4-Fluorobenzyl)carbonyl]amino-8-(3-phenylpropy...)
Affinity DataKi:  726nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed