BDBM50298550 5-[(4-Biphenylmethyl)carbonyl]amino-8-n-butyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine::CHEMBL573360

SMILES CCCCn1cc2c(n1)nc(NC(=O)Cc1ccc(cc1)-c1ccccc1)n1nc(nc21)-c1ccco1

InChI Key InChIKey=ZGRPHXBYYFJHFB-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50298550   Sort by

TargetAdenosine receptor A2b(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50298550(5-[(4-Biphenylmethyl)carbonyl]amino-8-n-butyl-2-(2...)
Affinity DataIC50: 8.63E+3nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-induced adenylyl cyclase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50298550(5-[(4-Biphenylmethyl)carbonyl]amino-8-n-butyl-2-(2...)
Affinity DataKi:  39.6nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50298550(5-[(4-Biphenylmethyl)carbonyl]amino-8-n-butyl-2-(2...)
Affinity DataKi:  189nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50298550(5-[(4-Biphenylmethyl)carbonyl]amino-8-n-butyl-2-(2...)
Affinity DataKi:  381nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed