BDBM50298708 CHEMBL574539::[3H]A-804598

SMILES C[C@H](NC(NC#N)=Nc1cccc2ncccc12)c1ccccc1

InChI Key InChIKey=PQYCRDPLPKGSME-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50298708   

TargetP2X purinoceptor 7(Mouse)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50298708([3H]A-804598 | CHEMBL574539)
Affinity DataIC50: 9nMAssay Description:Antagonist activity against mouse P2X7R expressed in human 1321N1 cell membrane incubated for 1 hrs by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50298708([3H]A-804598 | CHEMBL574539)
Affinity DataIC50: 10nMAssay Description:Binding affinity at human P2X7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Rat)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50298708([3H]A-804598 | CHEMBL574539)
Affinity DataIC50: 10nMAssay Description:Binding affinity at rat P2X7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Mouse)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50298708([3H]A-804598 | CHEMBL574539)
Affinity DataIC50: 10nMAssay Description:Binding affinity at mouse P2X7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Rat)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50298708([3H]A-804598 | CHEMBL574539)
Affinity DataIC50: 10nMAssay Description:Antagonist activity against rat P2X7R expressed in human 1321N1 cell membrane incubated for 1 hrs by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50298708([3H]A-804598 | CHEMBL574539)
Affinity DataIC50: 11nMAssay Description:Antagonist activity against human P2X7R expressed in human 1321N1 cell membrane incubated for 1 hrs by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed