BDBM50299761 CHEMBL574050::N-(3-fluoro-4-(7-methoxy-6-(3-morpholinopropoxy)quinolin-4-yloxy)phenyl)-3-(4-fluorophenyl)-2-oxoimidazolidine-1-carboxamide

SMILES COc1cc2nccc(Oc3ccc(NC(=O)N4CCN(C4=O)c4ccc(F)cc4)cc3F)c2cc1OCCCN1CCOCC1

InChI Key InChIKey=XETYZWDPAUDSEG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299761   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50299761(CHEMBL574050 | N-(3-fluoro-4-(7-methoxy-6-(3-morph...)
Affinity DataIC50:  40nMAssay Description:Inhibition of GST-tagged c-Met expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50299761(CHEMBL574050 | N-(3-fluoro-4-(7-methoxy-6-(3-morph...)
Affinity DataIC50:  30nMAssay Description:Inhibition of TPR-Met assessed as autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed