BDBM50300840 CHEMBL565753::N,N-Dimethyl-N-{2-[3-(thien-2-ylsulfonyl)-1Hpyrrolo[2,3-b]pyridin-1-yl]ethyl}amine

SMILES CN(C)CCn1cc(c2cccnc12)S(=O)(=O)c1cccs1

InChI Key InChIKey=UMIQCSRFYTVZEC-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300840   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300840(N,N-Dimethyl-N-{2-[3-(thien-2-ylsulfonyl)-1Hpyrrol...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300840(N,N-Dimethyl-N-{2-[3-(thien-2-ylsulfonyl)-1Hpyrrol...)
Affinity DataEC50:  154nMAssay Description:Agonist activity at human cloned 5HT6 receptor expressed in HeLa cells assessed as induction of adenylyl cyclase activity by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed