BDBM50301022 (+)-9-fluoropropyl-dihydrotetrabenazine::CHEMBL579217

SMILES COc1cc2[C@H]3C[C@@H](O)[C@H](CC(C)C)CN3CCc2cc1OCCCF

InChI Key InChIKey=GNKGXQHHUUEYQV-BHIYHBOVSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50301022   

TargetSynaptic vesicular amine transporter(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50301022((+)-9-fluoropropyl-dihydrotetrabenazine | CHEMBL57...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [125I]-iodovinyl-TBZ from VMAT2 in rat striatal homogenate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSynaptic vesicular amine transporter(Human)
Key Laboratory of Radiopharmaceuticals (Beijing Normal University)

Curated by ChEMBL
LigandPNGBDBM50301022((+)-9-fluoropropyl-dihydrotetrabenazine | CHEMBL57...)
Affinity DataKi:  0.100nMAssay Description:Binding affinity to VMAT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSynaptic vesicular amine transporter(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50301022((+)-9-fluoropropyl-dihydrotetrabenazine | CHEMBL57...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [125I]-iodovinyl-TBZ from VMAT2 in rat striatal membrane homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSynaptic vesicular amine transporter(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50301022((+)-9-fluoropropyl-dihydrotetrabenazine | CHEMBL57...)
Affinity DataKi:  0.360nMAssay Description:Displacement of [3H]-DTBZ from VMAT2 in rat striatal membrane homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed