BDBM50301246 4-guanidino-N-(4-(2-(2-hydroxy-2-(6-hydroxy-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-8-yl)ethylamino)-2-methylpropyl)phenyl)butanamide::CHEMBL565770

SMILES CC(C)(Cc1ccc(NC(=O)CCCN=C(N)N)cc1)NCC(O)c1cc(O)cc2c1OCC(=O)N2

InChI Key InChIKey=DWWUCPBOSXEXOB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301246   

TargetBeta-2 adrenergic receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301246BDBM50301246(4-guanidino-N-(4-(2-(2-hydroxy-2-(6-hydroxy-3-oxo-...)
Affinity DataEC50:  4.10nMAssay Description:Agonist activity at human beta2 adrenoceptor expressed in CHOK1 cell assessed as increase of intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301246BDBM50301246(4-guanidino-N-(4-(2-(2-hydroxy-2-(6-hydroxy-3-oxo-...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human beta-1 adrenoceptor expressed in CHOK1 cell assessed as increase of intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed