BDBM50301542 4-fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide::CHEMBL569270
SMILES CNc1cc(ncn1)-c1csc(n1)N(C)C(=O)c1ccc(F)cc1
InChI Key InChIKey=UTPGRZGMQVAYAA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50301542
Affinity DataKi: 7.90E+3nMAssay Description:Binding affinity to human mGluR5 by PDSP assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human dopamine D2 receptor by PDSP assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Mental Health
Curated by ChEMBL
National Institute of Mental Health
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human sigma-1 receptor by PDSP assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human histamine H1 receptor by PDSP assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human TSPO receptor by PDSP assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human 5-HT3 receptor by PDSP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at human mGluR1 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90E+3nMAssay Description:Antagonist activity at human mGluR5 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair