BDBM50301641 CHEMBL585851::trans-3-Oxo-N-(5-phenylpyrimidin-2-yl)-3H-spiro[7-aza-2-benzofuran-1,1'-cyclohexane]-4'-carboxamide::trans-5'-oxo-N-(5-phenylpyrimidin-2-yl)-5'H-spiro[cyclohexane-1,7'-furo[3,4-b]pyridine]-4-carboxamide

SMILES O=C1O[C@]2(CC[C@H](C(=O)Nc3ncc(-c4ccccc4)cn3)CC2)c2ncccc21

InChI Key InChIKey=FJAKPAPUGHHPRR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301641   

TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301641BDBM50301641(trans-3-Oxo-N-(5-phenylpyrimidin-2-yl)-3H-spiro[7-...)
Affinity DataIC50: 2.90nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301641BDBM50301641(trans-3-Oxo-N-(5-phenylpyrimidin-2-yl)-3H-spiro[7-...)
Affinity DataIC50: 2.90nMAssay Description:Displacement of [125I]PYY from human recombinant Y5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed