BDBM50301642 CHEMBL567495::trans-N-(5-(2-fluorophenyl)pyrimidin-2-yl)-3'-oxo-3'H-spiro[cyclohexane-1,1'-furo[3,4-c]pyridine]-4-carboxamide

SMILES O=C1O[C@]2(CC[C@H](C(=O)Nc3ncc(-c4ccccc4F)cn3)CC2)c2ccncc21

InChI Key InChIKey=YEGUVPNKCAHYEZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50301642   

TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301642BDBM50301642(trans-N-(5-(2-fluorophenyl)pyrimidin-2-yl)-3'-oxo-...)
Affinity DataIC50: 1.5nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301642BDBM50301642(trans-N-(5-(2-fluorophenyl)pyrimidin-2-yl)-3'-oxo-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NPY Y2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301642BDBM50301642(trans-N-(5-(2-fluorophenyl)pyrimidin-2-yl)-3'-oxo-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NPY Y1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301642BDBM50301642(trans-N-(5-(2-fluorophenyl)pyrimidin-2-yl)-3'-oxo-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NPY Y4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed