BDBM50301768 CHEMBL584897::isopropyl 6-(4-chlorobenzoyl)-2-cyano-4,4-dimethyl-1,4,5,6,7,8-hexahydropyrrolo[3,2-d]azepine-8-carboxylate

SMILES CC(C)OC(=O)C1CN(C(=O)c2ccc(Cl)cc2)CC(C)(C)c2cc(C#N)[nH]c21

InChI Key InChIKey=SYXYQNKRRUXROU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301768   

TargetBile acid receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301768BDBM50301768(isopropyl 6-(4-chlorobenzoyl)-2-cyano-4,4-dimethyl...)
Affinity DataEC50:  4.10E+3nMAssay Description:Agonist activity at gal4-tagged human FXR-ligand binding domain expressed in human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed