BDBM50302261 (R)-N-(4-(3,4-dimethoxyphenyl)-4-(4-(4-ethylpiperazin-1-yl)-1-oxoisoindolin-2-yl)butyl)-N-methylthiophene-2-sulfonamide::CHEMBL571535
SMILES CCN1CCN(CC1)c1cccc2C(=O)N(Cc12)[C@H](CCCN(C)S(=O)(=O)c1cccs1)c1ccc(OC)c(OC)c1
InChI Key InChIKey=PKYMOQVCDUAWSB-AREMUKBSSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50302261
TargetUrotensin-2 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Antagonist activity at urotensin 2 receptor in human RMS13 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobilization aft...More data for this Ligand-Target Pair
TargetUrotensin-2 receptor(Rat)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...More data for this Ligand-Target Pair