BDBM50302942 2-(N-tert-Butylamino)-3'-methylpropiophenone::2-(tert-butylamino)-1-m-tolylpropan-1-one::CHEMBL566832
SMILES CC(NC(C)(C)C)C(=O)c1cccc(C)c1
InChI Key InChIKey=YDGOUEKZXBLUDG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50302942
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]RTI55 from cloned human SERT expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]RTI55 from cloned human NET expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]RTI55 from cloned human DAT expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >100nMAssay Description:Inhibition of [3H]serotonin uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human alpha4beta2 nAChR receptor expressed in human SH-SY5Y cells assessed as inhibition of carbamylcholine-induced 86Rb+ effl...More data for this Ligand-Target Pair