BDBM50303527 (2,2,3,3-Tetramethylcyclopropyl)(1-(4,4,4-trifluorobutyl)-1Hindol-3-yl)methanone::CHEMBL569082

SMILES CC1(C)C(C(=O)c2cn(CCCC(F)(F)F)c3ccccc23)C1(C)C

InChI Key InChIKey=PEXYKZYTXIEEOB-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50303527   

TargetCannabinoid receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50303527((2,2,3,3-Tetramethylcyclopropyl)(1-(4,4,4-trifluor...)
Affinity DataKi:  0.0900nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50303527((2,2,3,3-Tetramethylcyclopropyl)(1-(4,4,4-trifluor...)
Affinity DataKi:  0.830nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cell membrane incubated for 1 hr by liquid scintillation spectrophotometric anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50303527((2,2,3,3-Tetramethylcyclopropyl)(1-(4,4,4-trifluor...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50303527((2,2,3,3-Tetramethylcyclopropyl)(1-(4,4,4-trifluor...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membrane incubated for 1 hr by liquid scintillation spectrophotometric a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50303527((2,2,3,3-Tetramethylcyclopropyl)(1-(4,4,4-trifluor...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed