BDBM50303583 CHEMBL570874::Cyclohexyl(1-(2-morpholinoethyl)-1H-indol-3-yl)methanone

SMILES O=C(C1CCCCC1)c1cn(CCN2CCOCC2)c2ccccc12

InChI Key InChIKey=BKMZISGAQBQGPE-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50303583   

TargetCannabinoid receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303583BDBM50303583(Cyclohexyl(1-(2-morpholinoethyl)-1H-indol-3-yl)met...)
Affinity DataEC50:  86nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303583BDBM50303583(Cyclohexyl(1-(2-morpholinoethyl)-1H-indol-3-yl)met...)
Affinity DataKi:  138nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303583BDBM50303583(Cyclohexyl(1-(2-morpholinoethyl)-1H-indol-3-yl)met...)
Affinity DataKi:  1.63E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed