BDBM50303999 4-(4-Methylpiperazin-1-yl)-2-(2-naphthylmethyl)-1H-benzimidazole::CHEMBL566219

SMILES C(c1nc2c(cccc2[nH]1)N1CCNCC1)c1ccc2ccccc2c1

InChI Key InChIKey=LUCKOIPIDNSDGW-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50303999   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50303999(4-(4-Methylpiperazin-1-yl)-2-(2-naphthylmethyl)-1H...)
Affinity DataKi:  17nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50303999(4-(4-Methylpiperazin-1-yl)-2-(2-naphthylmethyl)-1H...)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50303999(4-(4-Methylpiperazin-1-yl)-2-(2-naphthylmethyl)-1H...)
Affinity DataKi: >500nMAssay Description:Displacement of [3H]LSD from human 5HT7 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed