BDBM50304000 4-(4-Methylpiperazin-1-yl)-2-(1-naphthylmethyl)-1H-benzimidazole::CHEMBL566218

SMILES CN1CCN(c2cccc3[nH]c(Cc4cccc5ccccc45)nc23)CC1

InChI Key InChIKey=DZCOFFSCUNYLGZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50304000   

Target5-hydroxytryptamine receptor 6(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304000BDBM50304000(4-(4-Methylpiperazin-1-yl)-2-(1-naphthylmethyl)-1H...)
Affinity DataKi:  27nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of serotonin-induced cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304000BDBM50304000(4-(4-Methylpiperazin-1-yl)-2-(1-naphthylmethyl)-1H...)
Affinity DataKi:  36.2nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304000BDBM50304000(4-(4-Methylpiperazin-1-yl)-2-(1-naphthylmethyl)-1H...)
Affinity DataKi: >500nMAssay Description:Displacement of [3H]LSD from human 5HT7 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed