BDBM50304335 3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane::CHEMBL608710

SMILES Cn1c(cc2ccccc12)C(=O)OC1C[C@H]2CC[C@H](C1)N2

InChI Key InChIKey=CBUHKJLQRNBVRE-CHWSQXEVSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50304335   

Target5-hydroxytryptamine receptor 3A(RAT)
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50304335(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Affinity DataIC50:  25nMAssay Description:Displacement of [3H]granisectron from 5HT3 receptor in Wistar rat forebrainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycine receptor subunit alpha-1(RAT)
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50304335(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Affinity DataIC50:  33.9nMAssay Description:Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycine receptor subunit alpha-1(RAT)
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50304335(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Affinity DataIC50:  11.5nMAssay Description:Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycine receptor subunit alpha-1(RAT)
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50304335(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Affinity DataIC50:  70.8nMAssay Description:Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry in presence of 10 uM glycineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycine receptor subunit alpha-1(RAT)
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50304335(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Affinity DataIC50:  1.07nMAssay Description:Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry in presence of 10 uM glycineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycine receptor subunit alpha-1(RAT)
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50304335(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Affinity DataIC50:  135nMAssay Description:Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry in presence of 10 uM glycineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycine receptor subunit alpha-1(RAT)
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50304335(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Affinity DataIC50:  126nMAssay Description:Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed