BDBM50305263 2,8-Dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole::CHEMBL592752
SMILES CN1CCc2c(C1)c1cc(C)ccc1n2CCc1ccccc1
InChI Key InChIKey=IBUHDDLETPJVGP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50305263
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataKi: 0.153nMAssay Description:Binding affinity to 5-HT7 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataKi: 0.153nMAssay Description:Displacement of [3H]lysergic acid from 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:Binding affinity to histamine H1 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity to 5-HT2c receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity to 5-HT2C receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity to 5-HT2A receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity to 5-HT6 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity to 5-HT6 receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity to 5-HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
Affinity DataIC50: 146nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as reduction of histamine-induced intracellular calcium spike at phase 2...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataIC50: 158nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...More data for this Ligand-Target Pair