BDBM50305281 CHEMBL594649::[(1R,2R,6R,10S,11R,13S,15R,17R)-13-benzyl-6-hydroxy-4,17-dimethyl-5-oxo-15-(prop-1-en-2-yl)-12,14,18-trioxapentacyclo[11.4.1.0^{1,10}.0^{2,6}.0^{11,15}]octadeca-3,8-dien-8-yl]methyl 2-(acetyloxy)-2-(4-hydroxy-3-methoxyphenyl)acetate

SMILES C=C(C)[C@]12C[C@@H](C)[C@@]34O[C@](Cc5ccccc5)(O[C@@H]1[C@@H]3C=C(COC(=O)C(OC(C)=O)c1ccc(O)c(OC)c1)C[C@]1(O)C(=O)C(C)=C[C@@H]41)O2

InChI Key InChIKey=IPCJGABZAXBYMQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305281   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50305281BDBM50305281([(1R,2R,6R,10S,11R,13S,15R,17R)-13-benzyl-6-hydrox...)
Affinity DataEC50:  0.650nMAssay Description:Agonist activity at human TRPV1 expressed in HEK293 cells assessed as increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed