BDBM50305306 (3-(9-(1-benzylpiperidin-4-yl)-6-morpholino-9H-purin-2-yl)phenyl)methanol::CHEMBL589142
SMILES OCc1cccc(c1)-c1nc(N2CCOCC2)c2ncn(C3CCN(Cc4ccccc4)CC3)c2n1
InChI Key InChIKey=NXFHEWHRZWCTEI-UHFFFAOYSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50305306
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
Affinity DataIC50: 634nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
Affinity DataIC50: 634nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
Affinity DataIC50: 691nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of human PI3Kgamma by fluorescence polarization format assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kgamma by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
