BDBM50305343 4-(3'-Fluorophenyl)methyl-4-azahexacyclo[5.4.1.02,6.03,10.05,9.08,11]dodecan-3-ol::CHEMBL608560

SMILES OC12C3C4C5C3C(C3C5CC4C13)N2Cc1cccc(F)c1

InChI Key InChIKey=DUZFRLZTNIIHKJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50305343   

TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM50305343(4-(3'-Fluorophenyl)methyl-4-azahexacyclo[5.4.1.02,...)
Affinity DataKi:  151nMAssay Description:Displacement of [3H](+)-pentazocine from sigma-1 receptor in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50305343(4-(3'-Fluorophenyl)methyl-4-azahexacyclo[5.4.1.02,...)
Affinity DataKi:  153nMAssay Description:Binding affinity to sigma 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50305343(4-(3'-Fluorophenyl)methyl-4-azahexacyclo[5.4.1.02,...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to Alpha2C adrenoceptor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50305343(4-(3'-Fluorophenyl)methyl-4-azahexacyclo[5.4.1.02,...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed