BDBM50306020 3-(3-(8-chloro-2-isopropylimidazo[1,2-a]pyridin-3-yl)phenoxy)-N-methylbenzenesulfonamide::CHEMBL595917

SMILES CNS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(nc3c(Cl)cccn23)C(C)C)c1

InChI Key InChIKey=ZLCICKWEGSYHOX-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50306020   

TargetOxysterols receptor LXR-beta(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306020(3-(3-(8-chloro-2-isopropylimidazo[1,2-a]pyridin-3-...)
Affinity DataEC50:  1.61E+3nMAssay Description:Agonist activity at human Gal4-LBD fused LXRbeta LBD expressed in Huh7 cells by transient transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306020(3-(3-(8-chloro-2-isopropylimidazo[1,2-a]pyridin-3-...)
Affinity DataEC50:  530nMAssay Description:Displacement of [3H]T0901317 from human recombinant LXRalpha LBDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306020(3-(3-(8-chloro-2-isopropylimidazo[1,2-a]pyridin-3-...)
Affinity DataIC50:  7.5nMAssay Description:Displacement of [3H]T0901317 from human recombinant LXRalpha LBDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-beta(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306020(3-(3-(8-chloro-2-isopropylimidazo[1,2-a]pyridin-3-...)
Affinity DataIC50:  239nMAssay Description:Displacement of [3H]T0901317 from human recombinant LXRbeta LBDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed