BDBM50306046 3-(3-(8-chloro-2-isopropylimidazo[1,2-a]pyridin-3-yl)phenoxy)-N-(4-methoxybenzyl)-N-methylbenzenesulfonamide::CHEMBL595915

SMILES COc1ccc(CN(C)S(=O)(=O)c2cccc(Oc3cccc(c3)-c3c(nc4c(Cl)cccn34)C(C)C)c2)cc1

InChI Key InChIKey=IAVNBGWOUPTSOV-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50306046   

TargetOxysterols receptor LXR-beta(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306046(3-(3-(8-chloro-2-isopropylimidazo[1,2-a]pyridin-3-...)
Affinity DataIC50:  71nMAssay Description:Displacement of [3H]T0901317 from human recombinant LXRbeta LBDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306046(3-(3-(8-chloro-2-isopropylimidazo[1,2-a]pyridin-3-...)
Affinity DataEC50:  890nMAssay Description:Displacement of [3H]T0901317 from human recombinant LXRalpha LBDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306046(3-(3-(8-chloro-2-isopropylimidazo[1,2-a]pyridin-3-...)
Affinity DataIC50:  24nMAssay Description:Displacement of [3H]T0901317 from human recombinant LXRalpha LBDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-beta(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306046(3-(3-(8-chloro-2-isopropylimidazo[1,2-a]pyridin-3-...)
Affinity DataEC50:  930nMAssay Description:Agonist activity at human Gal4-LBD fused LXRbeta LBD expressed in Huh7 cells by transient transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed