BDBM50306203 2-(4-(1,4-diazepane-1-carbonyl)phenyl)-2H-indazole-7-carboxamide::CHEMBL596143

SMILES NC(=O)c1cccc2cn(nc12)-c1ccc(cc1)C(=O)N1CCCNCC1

InChI Key InChIKey=PDRUYQAWRBGOQZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306203   

TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50306203(2-(4-(1,4-diazepane-1-carbonyl)phenyl)-2H-indazole...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed