BDBM50306217 4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-morpholino-1H-pyrazole-3-carboxamide::CHEMBL594756

SMILES NC(=O)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)NN1CCOCC1

InChI Key InChIKey=AZRTYGZMNIRFGH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50306217   

TargetCannabinoid receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50306217(4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chl...)
Affinity DataIC50: 1.70nMAssay Description:Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50306217(4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chl...)
Affinity DataIC50: 7nMAssay Description:Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP-55940-induced GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50306217(4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chl...)
Affinity DataIC50: 7.90nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed