BDBM50306289 4-(1-butyl-3-(3-hydroxyphenyl)piperidin-3-yl)-N,N-diethylbenzamide::CHEMBL592907

SMILES CCCCN1CCCC(C1)(c1ccc(cc1)C(=O)N(CC)CC)c1cccc(O)c1

InChI Key InChIKey=RTMAZPQMEHLOAT-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50306289   

TargetDelta-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50306289(4-(1-butyl-3-(3-hydroxyphenyl)piperidin-3-yl)-N,N-...)
Affinity DataKi:  6.20nMAssay Description:Displacement of [125I]diprenorphine from human delta opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50306289(4-(1-butyl-3-(3-hydroxyphenyl)piperidin-3-yl)-N,N-...)
Affinity DataIC50: 55nMAssay Description:Antagonist activity at delta opioid receptor by GTPgammaS bunding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50306289(4-(1-butyl-3-(3-hydroxyphenyl)piperidin-3-yl)-N,N-...)
Affinity DataKi: >890nMAssay Description:Displacement of [125I]diprenorphine from human mu opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50306289(4-(1-butyl-3-(3-hydroxyphenyl)piperidin-3-yl)-N,N-...)
Affinity DataKi: >890nMAssay Description:Displacement of [125I]diprenorphine from human kappa opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed