BDBM50306292 CHEMBL605735::N,N-diethyl-4-(3-(3-hydroxyphenyl)-1-(thiazol-2-ylmethyl)piperidin-3-yl)benzamide

SMILES CCN(CC)C(=O)c1ccc(cc1)C1(CCCN(Cc2nccs2)C1)c1cccc(O)c1

InChI Key InChIKey=ZAKIMSJDFSDBER-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50306292   

TargetDelta-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50306292(N,N-diethyl-4-(3-(3-hydroxyphenyl)-1-(thiazol-2-yl...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [125I]diprenorphine from human delta opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50306292(N,N-diethyl-4-(3-(3-hydroxyphenyl)-1-(thiazol-2-yl...)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at delta opioid receptor by GTPgammaS bunding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50306292(N,N-diethyl-4-(3-(3-hydroxyphenyl)-1-(thiazol-2-yl...)
Affinity DataKi:  163nMAssay Description:Displacement of [125I]diprenorphine from human kappa opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50306292(N,N-diethyl-4-(3-(3-hydroxyphenyl)-1-(thiazol-2-yl...)
Affinity DataKi: >890nMAssay Description:Displacement of [125I]diprenorphine from human mu opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed