BDBM50306296 4-(1-(cyclopropylmethyl)-4-(3-hydroxyphenyl)piperidin-4-yl)-N,N-diethylbenzamide::CHEMBL595245

SMILES CCN(CC)C(=O)c1ccc(cc1)C1(CCN(CC2CC2)CC1)c1cccc(O)c1

InChI Key InChIKey=SFZRRWGLLPCDSK-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50306296   

TargetDelta-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50306296(4-(1-(cyclopropylmethyl)-4-(3-hydroxyphenyl)piperi...)
Affinity DataKi:  9nMAssay Description:Displacement of [125I]diprenorphine from human delta opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50306296(4-(1-(cyclopropylmethyl)-4-(3-hydroxyphenyl)piperi...)
Affinity DataIC50: 155nMAssay Description:Antagonist activity at delta opioid receptor by GTPgammaS bunding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50306296(4-(1-(cyclopropylmethyl)-4-(3-hydroxyphenyl)piperi...)
Affinity DataKi:  440nMAssay Description:Displacement of [125I]diprenorphine from human kappa opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50306296(4-(1-(cyclopropylmethyl)-4-(3-hydroxyphenyl)piperi...)
Affinity DataKi: >890nMAssay Description:Displacement of [125I]diprenorphine from human mu opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed