BDBM50306503 4,4,4-trifluoro-3-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylamino)-N-phenylbutanamide::CHEMBL602703
SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(CC(=O)Nc4ccccc4)C(F)(F)F)cc3F)c2s1
InChI Key InChIKey=ZXXJTQRLPRCGMZ-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50306503
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of TPR-fused Met autophosphorylation expressed in HEK293T cells after 150 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of c-MET in human A549 cells by wound healing assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Methylgene
Curated by ChEMBL
Methylgene
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Methylgene
Curated by ChEMBL
Methylgene
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant GST-fused VEGFR2 expressed in baculovirus infected Sf9 cells by DELFIAMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant GST-fused c-Met expressed in baculovirus infected high five cells by DELFIAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of c-MET in human DU145 cells by scattering assayMore data for this Ligand-Target Pair