BDBM50306515 4'-((5-(benzylcarbamoyl)-2,3-dimethyl-1H-indol-1-yl)methyl)biphenyl-2-carboxylic acid::CHEMBL602469
SMILES Cc1c(C)c2cc(ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)C(=O)NCc1ccccc1
InChI Key InChIKey=HOWMTYZTQKZIEQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50306515
TargetPeroxisome proliferator-activated receptor gamma(Human)
The Scripps Research Institute
US Patent
The Scripps Research Institute
US Patent
Affinity DataIC50: 1nMAssay Description:The assay was performed according to manufacturer protocol. A mixture of nM GST-PPARG-LBD, 5 nM Tb-GST-antibody, 5 nM Fluormone Pan-PPAR Green, and s...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of radiolabled GW2433 from human PPARdelta ligand binding domain expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of radiolabled GW2433 from human PPARalpha ligand binding domain expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARdelta expressed in african green monkey CV1 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
The Scripps Research Institute
US Patent
The Scripps Research Institute
US Patent
Affinity DataIC50: 1nMAssay Description:Binding affinity to GST-tagged PPAR-gamma-LBD (unknown origin) after 2 hrs by Lantha screen assay using fluormone Pan-PPAR green probeMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
The Scripps Research Institute
US Patent
The Scripps Research Institute
US Patent
Affinity DataEC50: 47nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey CV1 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
The Scripps Research Institute
US Patent
The Scripps Research Institute
US Patent
Affinity DataIC50: 41nMAssay Description:Displacement of radiolabled ((5-{4-[Methyl-pyridin-2yl-amino)-ethoxy]-benzyl}-thiazolidine-2,4-dione) from human PPARgamma ligand binding domain expr...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
The Scripps Research Institute
US Patent
The Scripps Research Institute
US Patent
Affinity DataEC50: 300nMAssay Description:Transactivation of human PPARgamma in HEK293T cells after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey CV1 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair