BDBM50306629 CHEMBL606621::cis-1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(4-hydroxycyclohexyl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)-3-methylurea

SMILES CNC(=O)Nc1ccc(-c2nc(N3CC4CCC(C3)O4)c3cnn([C@H]4CC[C@@H](O)CC4)c3n2)cc1

InChI Key InChIKey=LQBQQAXIISEIGM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50306629   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306629BDBM50306629(cis-1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50306629BDBM50306629(cis-1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-...)
Affinity DataIC50: 227nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed