BDBM50307153 2,4-Diamino-5-methyl-6-(3',5'-dimethylphenylthio)pyrrolo[2,3-d]pyrimidine::CHEMBL596742

SMILES Cc1c(Sc2cc(C)cc(C)c2)[nH]c2nc(N)nc(N)c12

InChI Key InChIKey=CHTGFAJLGYOSEX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307153   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50307153(2,4-Diamino-5-methyl-6-(3',5'-dimethylphenylthio)p...)
Affinity DataIC50: 572nMAssay Description:Inhibition of Toxoplasma gondii DHFR using dihydrofolic acid substrate and NADPH cofactor by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50307153(2,4-Diamino-5-methyl-6-(3',5'-dimethylphenylthio)p...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactor by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed